Government Bans 156 Fixed-Dose Combination Drugs Due to Health Risks

The government has banned 156 fixed-dose combination (FDC) drugs, including popular antibacterial medicines, due to potential health risks. These drugs, comprising combinations of multiple active ingredients, were deemed 'irrational' and lacking therapeutic justification by an expert committee and the Drugs Technical Advisory Board. The ban aims to protect public health.

The government has issued a ban on 156 fixed-dose combination (FDC) drugs, which include commonly used antibacterial medicines for conditions such as fever, cold, and allergies. Authorities cited potential health risks associated with these medications.

FDC drugs are those that contain combinations of two or more active ingredients. A recent gazette notification from the Union Health Ministry dated August 12 listed several banned combinations, including the popular 'Aceclofenac 50mg + Paracetamol 125mg tablet', used for pain relief and manufactured by leading pharmaceutical companies. The ban also covers Mefenamic Acid + Paracetamol Injection and other similar combinations.

The Central government stated that safer alternatives exist for these risky FDC drugs, based on the findings of an Expert Committee and the Drugs Technical Advisory Board (DTAB). The committee and DTAB concluded that the banned FDCs lacked therapeutic justification and could pose health risks. Consequently, it was deemed necessary to prohibit their manufacture, sale, and distribution to safeguard public health.

(With inputs from agencies.)