Breakthrough Nasal Spray Targets Alzheimer's Tau Proteins

Scientists at the University of Texas Medical Branch have developed a nasal spray to eliminate tau proteins associated with Alzheimer's disease. Tests on mice showed significant memory improvement and reduced tau accumulation. This breakthrough could pave the way for non-invasive treatment of neurodegenerative diseases if successful in human trials.

Scientists at the University of Texas Medical Branch have made a significant breakthrough, developing a nasal spray aimed at eliminating tau proteins linked to Alzheimer's disease. Thus far, trials in mice have shown promising results, indicating not only a reduction in tau build-up but also notable memory improvements.

Most existing treatments focus on amyloid proteins, but this innovative spray specifically targets tau proteins, which have been harder to reach due to their accumulation inside neurons. This has hindered progress, as prior treatments struggled to penetrate the necessary areas within brain cells.

The remarkable nasal spray offers a non-invasive delivery method of antibodies directly to the brain. If successful in human trials, it could have far-reaching implications for treating multiple neurodegenerative diseases affected by tau accumulation.

(With inputs from agencies.)